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self-complementary (sc) aav vectors  (Biopharm GmbH)

 
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    Biopharm GmbH self-complementary (sc) aav vectors
    Self Complementary (Sc) Aav Vectors, supplied by Biopharm GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/self+complementary+aav+vector/self+complementary++sc++aav+vectors/pm25615882-171-10-42
    Average 90 stars, based on 1 article reviews
    self-complementary (sc) aav vectors - by Bioz Stars, 2026-11
    90/100 stars

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    Increased long-term specificity and efficiency for the minimal hIBA1a promoter when packaged in scAAV (A) Schematic diagram of the experimental procedure. scAAV5 virus with the hIBA1a promoter was injected into sham mice or mice with L-NIO-induced stroke. Brains were analyzed 1 week or 4 weeks later. (B) Representative confocal images showing marker expression for the indicated conditions. Scale bars, 50 μm. (C) Quantifications showing microglia-specificity of GFP expression for the indicated conditions (mean ± SEM; n = 3 mice per group). (D) Quantifications showing microglia transduction efficiency for the indicated conditions (mean ± SEM; n = 3 mice per group).

    Journal: iScience

    Article Title: Simple and highly specific targeting of resident microglia with adeno-associated virus

    doi: 10.1016/j.isci.2024.110706

    Figure Lengend Snippet: Increased long-term specificity and efficiency for the minimal hIBA1a promoter when packaged in scAAV (A) Schematic diagram of the experimental procedure. scAAV5 virus with the hIBA1a promoter was injected into sham mice or mice with L-NIO-induced stroke. Brains were analyzed 1 week or 4 weeks later. (B) Representative confocal images showing marker expression for the indicated conditions. Scale bars, 50 μm. (C) Quantifications showing microglia-specificity of GFP expression for the indicated conditions (mean ± SEM; n = 3 mice per group). (D) Quantifications showing microglia transduction efficiency for the indicated conditions (mean ± SEM; n = 3 mice per group).

    Article Snippet: The self-complementary AAV (scAAV) vectors were based on the scAAV-CAG-GFP vector (Addgene #83279) by replacing the CAG promoter with the hIBA1 promoter.

    Techniques: Virus, Injection, Marker, Expressing, Transduction

    Journal: iScience

    Article Title: Simple and highly specific targeting of resident microglia with adeno-associated virus

    doi: 10.1016/j.isci.2024.110706

    Figure Lengend Snippet:

    Article Snippet: The self-complementary AAV (scAAV) vectors were based on the scAAV-CAG-GFP vector (Addgene #83279) by replacing the CAG promoter with the hIBA1 promoter.

    Techniques: Recombinant, Software